
Treatment-Resistant Depression Orlando
When standard antidepressants haven't worked, specialized care makes the difference. Our board-certified psychiatrists in Orlando offer advanced medication strategies, augmentation therapies, and comprehensive evaluations for treatment-resistant depression. Same-week appointments available.
Get Specialized TRD Care
Get Specialized TRD Care
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Specialized Care for Treatment-resistant Depression in Orlando
Treatment-resistant depression (TRD) is defined as depression that has not responded adequately to at least two different antidepressant medications taken at proper doses for sufficient duration. If you've tried multiple medications without meaningful relief, you're not out of options. Our board-certified psychiatrists in Orlando specialize in advanced strategies for treatment-resistant depression.
At Empathy Health Clinic, we take a comprehensive approach to TRD. This begins with a thorough re-evaluation of your diagnosis — because sometimes what appears to be treatment-resistant depression is actually a misdiagnosed condition like bipolar disorder, thyroid dysfunction, or a co-occurring anxiety disorder. From there, we develop an individualized plan that may include medication augmentation, switching strategies, combination therapy, or referral for advanced treatments like TMS.
What We Evaluate & Treat in Orlando, FL
Advanced Depression Treatment Options
Comprehensive Re-Evaluation
A thorough diagnostic reassessment to confirm your diagnosis, rule out misdiagnosed conditions (like bipolar disorder or thyroid issues), and identify factors that may be limiting your response to treatment.
Medication Augmentation & Switching
Expert medication strategies including augmentation with atypical antipsychotics, lithium, thyroid hormone, or combination antidepressant therapy. We stay current with the latest evidence-based approaches.
Pharmacogenomic Testing
Genetic testing to understand how your body metabolizes psychiatric medications. This can reveal why certain antidepressants haven't worked and guide selection of medications more likely to be effective for you.
TMS Referral & Coordination
Transcranial Magnetic Stimulation (TMS) is an FDA-approved, non-invasive treatment for TRD. We evaluate candidacy, provide referrals to TMS providers, and coordinate your ongoing psychiatric care.
Why Choose Our Trd Specialists?
Specialized Expertise
Our psychiatrists have specific experience treating treatment-resistant depression and stay current with the latest research, including novel medications, augmentation strategies, and emerging therapies.
Evidence-Based Approach
We follow established clinical guidelines for TRD management, including the STAR*D study protocol and APA treatment algorithms, while also considering innovative approaches supported by current research.
Compassionate, Patient Care
We understand the frustration and hopelessness that can come with treatment-resistant depression. Our approach is collaborative, empathetic, and focused on finding solutions — even when previous treatments have failed.
Frequently Asked Questions - Mental Health Services
Medical References
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Why Patients Trust Empathy Health Clinic
Licensed Professionals
Board-certified psychiatrists and licensed therapists
HIPAA Compliant
Your privacy and confidentiality are protected
Insurance Accepted
We accept most major insurance plans
Same-Week Appointments
Fast access to care when you need it most
Featured on Psychology Today
Verified provider directory listing
Listed on GoodTherapy
Trusted mental health resource platform
Evidence-Based Treatment
Scientifically proven therapeutic approaches
Compassionate Care
Non-judgmental, patient-centered approach






